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The other, more superficial, portion of the diverticulum, on the other
hand, becomes the ureter. The ureter opens at first into the
hind-end of the Wolffian duct; after the sixth week it separates from
the Wolffian duct, and opens independently into the part of the cloaca which ultimately
becomes the urinary bladder. In the outer part of the intermediate mesoderm, immediately under the ectoderm, in the region from the fifth cervical segment to the third thoracic segment, a series of short evaginations from each segment grows dorsally and extends caudally,
fusing successively from before backward to form the pronephric duct.
The ureteric bud subsequently grows into the latter mass, forming
the parts of the nephron. One end grows toward and finally opens into the Wolffian duct, the other dilates and is invaginated by
a tuft of capillary bloodvessels to form a glomerulus.
Each kidney originates as a ureteric bud from the caudal end of the Wolffian duct, which, in turn, originates from intermediate mesoderm.
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